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#1. A Registered Report of Error-Related Negativity and Reward Positivity as Biomarkers of Depression: P-Curving the Evidence
Peter E. Clayson, Kaylie A. Carbine, Michael J. Larson
Performance-monitoring event-related brain potentials (ERPs), such as the error-related negativity (ERN) and reward positivity (RewP), are advocated as biomarkers of depression symptoms and risk. However, a recent meta-analysis indicated effect size heterogeneity in the ERN and RewP literatures. Hence, advocating these ERPs as biomarkers of depression might be premature or possibly misguided due to the selective reporting of significant analyses on the part of researchers (e.g., p-hacking or omission of non-significant findings). The present study quantified the degree of selective reporting and the evidential value for a true relationship between depression and ERN and RewP using a p-curve analysis. We predicted that the ERN and RewP literatures would fail to show evidential value for a relationship between each ERP and depression. Contrary to expectations, both literatures showed evidential value, albeit weak. The statistical power of the included ERN studies was between 20% and 25%, and the statistical power of the RewP was...
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NIMH_RDoC: 'A Registered Report of ERN and RewP as Biomarkers of Depression: P-Curving the Evidence' - https://t.co/boJRlCLw2s by @clayson_peter, Kaylie Carbine, & @mjlarson29 "....both literatures showed evidential value, albeit weak." https://t.co/0IlWQo1ORD
ugpavlov: RT @NIMH_RDoC: 'A Registered Report of ERN and RewP as Biomarkers of Depression: P-Curving the Evidence' - https://t.co/boJRlCLw2s by @clay…
clayson_peter: RT @NIMH_RDoC: 'A Registered Report of ERN and RewP as Biomarkers of Depression: P-Curving the Evidence' - https://t.co/boJRlCLw2s by @clay…
mjlarson29: RT @NIMH_RDoC: 'A Registered Report of ERN and RewP as Biomarkers of Depression: P-Curving the Evidence' - https://t.co/boJRlCLw2s by @clay…
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Total Words: 20543
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