Top 10 Biorxiv Papers Today in Scientific Communication And Education


1.998 Mikeys
#1. Thiel Embalming Pre-Frozen Cadavers: A Mouse Model
Murad Alshehry, Mostafa Kandil, Raed Alzahrani, Roger Soames
Thiel embalming has been gaining a great deal of worldwide attention. Its long-lasting life-like quality enables multiple applications in surgical training programs. The standard process of Thiel embalming, which involves perfusion of embalming fluid in fresh cadavers through cannulation of the arterial and venous systems could be difficult in some areas of the world where fresh body donation rates are low or banned. This study will assess the ability to Thiel embalm fresh frozen mice as an animal model as a solution for the lack of fresh cadavers. The ability of Thiel embalming frozen tissue would enable areas in the world where they do not have access to recently diseased donated cadavers. The study was ethically approved King Fahad Medical City Institutional Review Board. The 20 Mice cadavers were ethically gained from the university of Dundee animal house. They were euthanized ethically by carbon dioxide. They were handled by following the university's ethical code. The mice were split into 4 groups with 5 mice for each group,...
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biorxivpreprint: Thiel Embalming Pre-Frozen Cadavers: A Mouse Model https://t.co/2K1pDfhmCX #bioRxiv
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Authors: 4
Total Words: 3862
Unqiue Words: 1351

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#2. Tackling the research capacity challenge in Africa: An overview of African-led approaches to strengthen research capacity
Lem N Ngongalah, Ngwa N Rawlings, Emerson N Wepngong, James M Musisi, Claude N Ngwayu, Sharon Mumah
Background: Improved capacity for research is a valuable and sustainable means of advancing health and development in Africa. Local leadership in research capacity strengthening is important for developing contextually appropriate programs that increase locally-driven research, and improve Africa's ability to adapt and use scientific knowledge. This study provides an overview of African organisations that aim to strengthen research capacity in Africa, and the major initiatives or approaches being used for this purpose. Methods: A desk review of grey and published literature on research capacity strengthening in Africa was conducted, in addition to panel discussions on the determinants of research capacity in Africa. Data was analysed through thematic analysis and a framework developed by the Collaboration for Research Excellence in Africa (CORE Africa). Results: 11 organisations were identified, spread across South, Central, East and West Africa. The main approaches to improving research capacity were: providing opportunities for...
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Authors: 6
Total Words: 6348
Unqiue Words: 1845

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#3. A comparison of asymmetric before-after control impact (aBACI) and staircase experimental designs for testing the effectiveness of stream restoration
Tom M. Loughin, Stephen Nicholas Bennett, Nicolaas W. Bouwes
Before-after-control-impact (BACI) experimental designs are commonly used in large-scale experiments to test for environmental impacts. However, high natural variability of environmental conditions and populations, and low replication in both treatment and control areas in time and space hampers detection of responses. We compare the power of two asymmetric BACI (aBACI) designs to two staircase designs for detecting changes in juvenile steelhead (Oncorhynchus mykiss) abundance associated with a watershed-scale stream restoration experiment. We performed a simulation study to estimate the effect of a 25% increase in steelhead abundance using spatial and temporal estimates of variance from an ongoing study, and determined the power of each design. Experimental designs were then applied to three streams and each stream was composed of three 4 km long sections. We compared the power of a single treatment section in one stream (BACI-1), three simultaneous treatments of all sections in one stream (BACI-3), three sequential treatments in...
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biorxivpreprint: A comparison of asymmetric before-after control impact (aBACI) and staircase experimental designs for testing the effectiveness of stream restoration https://t.co/r64q8tMjT7 #bioRxiv
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Authors: 3
Total Words: 10926
Unqiue Words: 3267

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#4. Using vocational education to provide development solutions in the Pacific: An emphasis on climate change and health
Peni Hausia Havea, Amelia Siga, Titilia Rabuatoka, Apenisa Tagivetaua Tamani, Priya Devi, Ruci Senikula, Sarah L Hemstock, Helene Jacot Des Combes
This article reports on the results of the EU PacTVET project, which explored the use of Technical Vocational Education and Training (TVET) to provide a better understanding on the development solution for the impact of climate change on human health in the region. It describes the findings of a 2014-2018 project on the use of vocational education to provide development solutions in the Pacific with an emphasis on climate change and health. An exploratory design was used to investigate how vocational education developed solutions for climate change and health in the 15 Pacific African Caribbean and Pacific (P-ACP) countries: Cook Islands, Federated States of Micronesia (FSM), Fiji, Kiribati, Nauru, Niue, Palau, Papua New Guinea (PNG), Republic of Marshall Islands (RMI), Samoa, Solomon Islands, Timor-Leste, Tonga, Tuvalu and Vanuatu. Information collected via personal communication with relevant stakeholders, qualitative interviews, documents review, and survey (n=48) of youths and young women in Fiji. Data analysis was performed...
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Authors: 8
Total Words: 8990
Unqiue Words: 2828

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#5. Analysis and Correction of Inappropriate Image Duplication: The Molecular and Cellular Biology Experience
Arturo Casadevall, Elisabeth M Bik, Ferric C Fang, Amy Kullas, Roger J Davis
The present study analyzed 960 papers published in Molecular and Cellular Biology (MCB) from 2009-2016 and found 59 (6.1%) to contain inappropriately duplicated images. The 59 instances of inappropriate image duplication led to 42 corrections, 5 retractions and 12 instances in which no action was taken. Our experience suggests that the majority of inappropriate image duplications result from errors during figure preparation that can be remedied by correction. Nevertheless, ~10% of papers with inappropriate image duplications in MCB were retracted. If this proportion is representative, then as many as 35,000 papers in the literature are candidates for retraction due to image duplication. The resolution of inappropriate image duplication concerns after publication required an average of 6 h of journal staff time per published paper. MCB instituted a pilot program to screen images of accepted papers prior to publication that identified 12 manuscripts (14.5% out of 83) with image concerns in two months. The screening and correction of...
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StuartJRitchie: @AnnaLSchubert @ChrisExpTheNews Oh, I agree with the latter part of course! But I think what they mean is stuff like this: https://t.co/oxCkkdD5Ym
MicrobiomDigest: Our latest preprint with @ACasadevall1 @Amy_Kullas Ferric Fang, Roger J Davis. What are causes of duplications in science papers? Does screening manuscripts before publication affect frequency of duplicated images? How much extra time does that cost? https://t.co/0ifZMwkIHO
jflier: 6% of 960 papers in Mol Celll Biol (MCB) over period of years had inappropriate image duplication, and 10% of these were retracted. Important new study suggests extent of the problem and approaches to addressing it prospectively. https://t.co/VU4OOVQZ1v
Gjpvernant: Une analyse statistique sur les duplications d'images dans les gels d'électrophorèse. Une large majorité des duplications n'est pas de caractère frauduleux mais provient d'erreurs. Pourquoi les correctifs et les rétractions sont-ils si rares? https://t.co/kIawCov0T2
JelteWicherts: As many as 35,000 papers in the literature are candidates for retraction due to image duplication. https://t.co/L6Jd01uaMW
amylibrarian: Inappropriate image duplication is 1 of many reasons why articles are retracted. Image screening can catch these errors prior to publication. -> Analysis and Correction of Inappropriate Image Duplication: The Molecular and Cellular Biology Experience https://t.co/bZ0SGARA9G https://t.co/3rqPXzpErc
ACasadevall1: MCB study of inappropriately duplicated images published! Preprint available. First estimate of compromised papers in literature. Bad news: large number (35,000). Good news: small fraction of literature. Kudos to @MicrobiomDigest @Amy_Kullas @RogerJDavis1 https://t.co/16NYWAYAfd
psforscher: Analysis of 960 molecular and cellular biology papers finds that 6% contain inappropriate image duplications https://t.co/IBwxfmP6hH Of the papers with duplications, 71% were corrected, 8% retracted, and for 20%, no action was taken
dn_mason: "Our goal is to make sure that the science is correct, not to punish." Really interesting read on an estimated 35,000 (CI 6,584-86,911) problematic papers from @RetractionWatch https://t.co/aumpsIJrs8 And preprint @ https://t.co/ij74Fuzn0k
jtth: that is a very big number https://t.co/NfaAKMo1y2 https://t.co/48rsjkSMwe
sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ https://t.co/9Cf6LnMUZt
SBAmin: Bold headline from @RetractionWatch 35,000 (CI 6,584-86,911) papers are candidates for retraction due to image duplication. https://t.co/RTZkUs3Tn7 @biorxivpreprint https://t.co/ngMtBNUkCg ; Won't be surprised if #MachineLearning folks get on this to improve prediction accuracy
DaveFernig: Analysis and Correction of Inappropriate Image Duplication: The Molecular and Cellular Biology Experience https://t.co/t7b5Kn7laM An excellent paper and yes, we should trawl the literature and bin the rubbish
AtlasSpinalCare: “Doctored” photos falsify over 30,000 research studies! 😱 The problematic practice of #imagemanipulation has been steadily growing in academic circles over the years. A study conducted by #Stanford Microbiologist... https://t.co/dOv3kczHsb
BrianWeitzner: 35,000 possible retractions?? "Analysis and Correction of Inappropriate Image Duplication" https://t.co/t9jc78B87R
biOverlay: New #biOverlay: https://t.co/HtFFnzRPX6 AE: @GreeneScientist Reviewers: Daniel Ernesto Acuna (https://t.co/qX1xrsIoPb) and Anon Preprint: https://t.co/QE9JX6H9vP https://t.co/GO65fDvSEV
ReaDI_Columbia: "[M]ajority of inappropriate image duplications result from errors during figure preparation that can be remedied by correction" https://t.co/mthf1w2NTN check out the resources the @ReaDI_Columbia has on figure manipulation: https://t.co/KqUwRfefFC
Chemistae: @bphilhour Not sure why this seems so much more common in bio than other fields. Did you see the preprint study? 6% of 960 papers on bioRxiv had image issues. https://t.co/b6H97JNueW
Keszenman: @norabar @janarhertz @lsqui @JorgeBalmelli Reytaccion de articulos cientificos que tendria que suceder https://t.co/sIhs9qxPos https://t.co/xWd5W71y34
BejaLab: Analysis and Correction of Inappropriate Image Duplication: The Molecular and Cellular Biology Experience https://t.co/jI5KYm5bHn
antoryan: https://t.co/Xh1hMJ1nm4
gopizz: Analysis and Correction of Inappropriate Image Duplication: The Molecular and Cellular Biology Experience https://t.co/hH3jLCsumw
konamih: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
vhrcabral: https://t.co/FwfibwEVWK
kenjiitojp: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
ElekiTan: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
Slight_Bright: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
unicoder: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
Oui_mitaka: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
mrk3692: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
yumikoyamako: RT @sato51643335: またすごい論文が出ていますが、Retraction Watchが著者にインタビューしています。Bikさんのコメントは非常に思慮深いもので、健全な科学を目指すにはどうしたら良いのかを考えさせます。 https://t.co/3qbwQv5SvQ…
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Authors: 5
Total Words: 5462
Unqiue Words: 1894

0.0 Mikeys
#6. Mind the Gap: Identifying What Is Missed When Searching Only the Broad Scope with PubMed Clinical Queries
Edwin Vincent Sperr
Objective: PubMed Clinical Queries are subdivided into 'Broad' and 'Narrow' versions. These versions are tuned to maximize either retrieval or sensitivity using two different sets of keywords and MeSH headings. While a searcher might assume that all items retrieved by Filter name/Narrow would also be found in the set Filter name/Broad, this is not explicitly guaranteed. It is the purpose of this study to quantify the overlap between these two sets and confirm whether Filter/Narrow is always a subset of Filter/Broad. Methods: For each of the five PubMed Clinical Queries, PubMed was searched for citations matching the query Filter/Narrow NOT Filter/Broad. This number was compared with that for Filter/Broad to compute a 'degree of discordance' between the two sets. This process was then repeated for the MeSH headings for 'Medicine' and 'Diseases' as well as for a set of test searches. Results: Four of the five Clinical Queries returned citations using Filter/Narrow that were not found with Filter/Broad. Discordances between the sets...
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biorxivpreprint: Mind the Gap: Identifying What Is Missed When Searching Only the Broad Scope with PubMed Clinical Queries https://t.co/K5LTkxW7b8 #bioRxiv
edsperr: Do you use PubMed Clinical Queries on a regular basis? Check out my preprint -- Mind the Gap: Identifying What Is Missed When Searching Only the Broad Scope with PubMed Clinical Queries https://t.co/LxBm7xbAX2
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#7. Risk Factors Associated with Dengue Virus Infection in Guangdong Province: a Community-based Case-control Study
Jundi Liu, Xiaolu Tian, Yu Deng, Zhichneg Du, Tianzhu Liang, Yuantao Hao, dingmei zhang, Jundi Liu, Xiaolu Tian, Yu Deng, Zhicheng Du, Tianzhu Liang, Yuantao Hao and Dingmei Zhang
Background: Dengue fever is a mosquito-borne infectious disease, and it is now still epidemic in China, especially in Guangdong Province. Owing to the absence of dengue vaccination, effective preventive measure is critical for controlling of dengue fever. This study aimed to explore the individual risk factors of dengue virus infection in Guangdong Province, as well as to provide a scientific basis for prevention and supervision of dengue fever in future. Methods: A case-control study including 237 cases and 237 controls was performed. The data was collected from the epidemiological questionnaires. Univariate analysis was used for preliminary screening of 28 variables potentially related to dengue virus infection, and an unconditioned logistic regression analysis was used for multivariate analysis to analysis those statistically significant variables. Results: Multivariate analysis of the result showed three independent risk factors: activities in the park (odd ratio [OR]= 1.70, 95%CI 1.03 to 2.83), outdoor sports (OR= 1.67, 95%CI...
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biorxivpreprint: Risk Factors Associated with Dengue Virus Infection in Guangdong Province: a Community-based Case-control Study https://t.co/Cw0xkQfodT #bioRxiv
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Total Words: 7203
Unqiue Words: 2710

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#8. Nucleotides inclusion in pet food: effect of thermic treatment and shelf-life
Natalia Russo, Alessia Candellone, Davide Galaverna, Liviana Prola
A growing trend of nucleotides supplementation in pets is occurring in recent years with the final goal of reinforcing the immune system and promoting intestinal function. Despite that, data evaluating possible alterations of nucleotides during pet food processing are lacking. The aim of the study was to evaluate the recovery percentage of nucleotides in dry and canned food after processing and storage. Selected dry and canned feed were supplemented with 0.4/100 g dry matter basis of Prosol petMOD™. Recovery percentage in dry food was 75% and 74% at the end of technological process and a 12-month shelf-life, while in canned food it was 43% and 41%, respectively. These results support the hypothesis that N could be included during pet food process but industries have to increase the awareness about possible losses, especially in canned food.
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#9. IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE
Dina Lary, Aaron Calvert, Brigitte Nerlich, Joel Segal, Natalie Vaughan, Jacqueline Randle, Kim Hardie
Background: Numerous interventions have tried to improve healthcare workers hand hygiene compliance, however little attention has been paid to childrens and their visitors compliance. Aim: To increase childrens and visitors compliance using interactive educational interventions. Methods: This was an observational study of hand hygiene compliance before and after the introduction of educational interventions. Qualitative data in the form of Questionnaires and interviews was obtained. Findings: Hand hygiene compliance increased by 21.4% (P <0.001) following the educational interventions, with children's compliance reaching 40.8% and visitors' being 50.8%. Compliance varied depending on which of the five moments of hygiene was observed (P<0.001), with the highest compliance after body exposure (96%). Responses from questionnaires showed educational interventions raised awareness of the importance of hand hygiene (69%, 57%) compared to those who had not experienced the educational intervention (50%). Conclusion: Educational...
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biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
Bander1Khalil: Retweeted bioRxiv (@biorxivpreprint): IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/nVJPgZTmgf #bioRxiv https://t.co/nVJPgZTmgf
LaryDAB: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/H5r1hSH28Z @biorxivpreprint
ta5ta5_basha: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
Bander1Khalil: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
BandarTambousi: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
AlMalekaD: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
SaraLary96: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
TanaSultana: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
JawahirBugis: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
3mmar10: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
azlary: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
rmrmali2: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
lujy_k: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
LaryDAB: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
alsoso60: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
ThaisLouvain: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
AlaaJamj: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
shathagf: RT @biorxivpreprint: IMPROVING CHILDREN'S AND THEIR VISITORS' HAND HYGIENE COMPLIANCE https://t.co/6QivSldVrf #bioRxiv
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#10. Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results
Gil Alterovitz, Dennis A Dean, Carole Goble, Michael R Crusoe, Stian Soiland-Reyes, Amanda Bell, Anais Hayes, Anita Suresh, Anjan Purkayastha, Charles Hadley H King, Dan Taylor, Elaine Johanson, Elaine E Thompson, Eric Donaldson, Hiroki Morizono, Hsinyi Tsang, Jeet K Vora, Jeremy Goecks, Jianchao Yao, Jonas S Almeida, Jonathon Keeney, KanakaDurga Addepalli, Konstantinos Krampis, Krista Smith, Lydia Guo, Mark Walderhaug, Marco Schito, Matthew Ezewudo, Nuria Guimera, Paul Walsh, Robel Kahsay, Srikanth Gottipati, Timothy C Rodwell, Toby Bloom, Yuching Lai, Vahan Simonyan, Raja Mazumder
A personalized approach based on a patient's or pathogen's unique genomic sequence is the foundation of precision medicine. Genomic findings must be robust and reproducible, and experimental data capture should adhere to FAIR guiding principles. Moreover, effective precision medicine requires standardized reporting that extends beyond wet lab procedures to computational methods. The BioCompute framework (https://osf.io/zm97b/) enables standardized reporting of genomic sequence data provenance, including provenance domain, usability domain, execution domain, verification kit, and error domain. This framework facilitates communication and promotes interoperability. Bioinformatics computation instances that employ the BioCompute framework are easily relayed, repeated if needed and compared by scientists, regulators, test developers, and clinicians. Easing the burden of performing the aforementioned tasks greatly extends the range of practical application. Large clinical trials, precision medicine, and regulatory submissions require a...
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dennisadean2: An updated version of Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results https://t.co/1k6trMdbAl #BioCompute
HadleyKingIV: @bgrotan @soilandreyes https://t.co/ftiI1Mhcrw
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